Oscar hits the road to visit more than 10 cities

FILE - In this Feb. 26, 2012 file photo, an Oscar statue is seen on the red carpet before the 84th Academy Awards in Los Angeles. The Academy of Motion Picture Arts and Sciences says the golden statuette will visit at least 10 cities as part of its first national tour. Beginning Monday, Feb. 4, 2013, in New York City, the golden guy?s journey will be chronicled online. (AP Photo/Matt Sayles, File)

FILE - In this Feb. 26, 2012 file photo, an Oscar statue is seen on the red carpet before the 84th Academy Awards in Los Angeles. The Academy of Motion Picture Arts and Sciences says the golden statuette will visit at least 10 cities as part of its first national tour. Beginning Monday, Feb. 4, 2013, in New York City, the golden guy?s journey will be chronicled online. (AP Photo/Matt Sayles, File)

LOS ANGELES (AP) ? Oscar is going on a road trip.

The Academy of Motion Picture Arts and Sciences says one of the golden statuettes that are handed out at the Academy Awards will visit at least 10 cities as part of Oscar's first national tour.

Beginning Monday in New York City, the golden guy's journey will be chronicled online. Fans can follow the Oscar statue's progress and even make suggestions for stops along the way.

The statuette will make appearances in Philadelphia, Washington, D.C., Baltimore, Chicago, St. Louis, Kansas City, Mo., Houston, Dallas and Phoenix before arriving in Hollywood for the Academy Awards on Feb. 24. Fans in those cities will have a chance to pose for photos with the Oscar trophy.

___

Online:

http://www.oscars.org

Associated Press

Source: http://hosted2.ap.org/APDEFAULT/4e67281c3f754d0696fbfdee0f3f1469/Article_2013-01-29-Oscars-National%20Tour/id-f1a64651183a41e0b341670a16f33f55

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500px Returns To The iOS App Store, With Mature Content Warning And Photo Reporting Button

Toronto's 500px got its popular photo sharing iPhone app back on the iTunes App Store today, following a takedown that Apple said stemmed from multiple user complaints about pornographic material. The app returns with an age-gate warning, advising that the content in the app is for 17+ audiences, and also adds a new "Report Photo" button to help users quickly tag things they find offensive for potential removal from the network.

Source: http://feedproxy.google.com/~r/Techcrunch/~3/RBGCOZtkogM/

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Video: First Read Minute

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Source: http://video.msnbc.msn.com/nightly-news/50627664/

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Mysteries of spider silk strength unraveled

Jan. 27, 2013 ? Scientists at ASU are celebrating their recent success on the path to understanding what makes the fiber that spiders spin -- weight for weight -- at least five times as strong as piano wire. They have found a way to obtain a wide variety of elastic properties of the silk of several intact spiders' webs using a sophisticated but non-invasive laser light scattering technique.

"Spider silk has a unique combination of mechanical strength and elasticity that make it one of the toughest materials we know," said Professor Jeffery Yarger of ASU's Department of Chemistry and Biochemistry, and lead researcher of the study. "This work represents the most complete understanding we have of the underlying mechanical properties of spider silks."

Spider silk is an exceptional biological polymer, related to collagen (the stuff of skin and bones) but much more complex in its structure. The ASU team of chemists is studying its molecular structure in an effort to produce materials ranging from bulletproof vests to artificial tendons.

The extensive array of elastic and mechanical properties of spider silks in situ, obtained by the ASU team, is the first of its kind and will greatly facilitate future modeling efforts aimed at understanding the interplay of the mechanical properties and the molecular structure of silk used to produce spider webs.

The team published their results in a recent issue of Nature materials and their paper is titled "Non-invasive determination of the complete elastic moduli of spider silks."

"This information should help provide a blueprint for structural engineering of an abundant array of bio-inspired materials, such as precise materials engineering of synthetic fibers to create stronger, stretchier, and more elastic materials," explained Yarger.

Other members of Yarger's team, in ASU's College of Liberal Arts and Sciences, included Kristie Koski, at the time a postdoctoral researcher and currently a postdoctoral fellow at Stanford University, and ASU undergraduate students Paul Akhenblit and Keri McKiernan.

The Brillouin light scattering technique used an extremely low power laser, less than 3.5 milliwatts, which is significantly less than the average laser pointer. Recording what happened to this laser beam as it passed through the intact spider webs enabled the researchers to spatially map the elastic stiffnesses of each web without deforming or disrupting it. This non-invasive, non-contact measurement produced findings showing variations among discrete fibers, junctions and glue spots.

Four different types of spider's webs were studied. They included Nephila clavipes (pictured), A. aurantia ("gilded silver face"-common to the contiguous United States), L. Hesperus the western black widow and P. viridans the green lynx spider, the only spider included that does not build a web for catching prey but has major silk elastic properties similar to those of the other species studied.

The group also investigated one of the most studied aspects of orb-weaving dragline spider silk, namely supercontraction, a property unique to silk. Spider silk takes up water when exposed to high humidity. Absorbed water leads to shrinkage in an unrestrained fiber up to 50 percent shrinkage with 100 percent humidity in N. clavipes silk.

Their results are consistent with the hypothesis that supercontraction helps the spider tailor the properties of the silk during spinning. This type of behavior, specifically adjusting mechanical properties by simply adjusting water content, is inspirational from a bio-inspired mechanical structure perspective.

"This study is unique in that we can extract all the elastic properties of spider silk that cannot and have not been measured with conventional testing," concluded Yarger.

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Story Source:

The above story is reprinted from materials provided by Arizona State University.

Note: Materials may be edited for content and length. For further information, please contact the source cited above.

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Journal Reference:

1. Kristie J. Koski, Paul Akhenblit, Keri McKiernan, Jeffery L. Yarger. Non-invasive determination of the complete elastic moduli of spider silks. Nature Materials, 2013; DOI: 10.1038/nmat3549

Note: If no author is given, the source is cited instead.

Disclaimer: Views expressed in this article do not necessarily reflect those of ScienceDaily or its staff.

Source: http://feeds.sciencedaily.com/~r/sciencedaily/most_popular/~3/vTijetqY7Dw/130128104741.htm

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Video: Senate passes $50 billion Sandy aid package

>>> it has been exactly three months since hurricane sandy tore up the east coast , and finally tonight, after a four-week delay, the senate gave final approval to a $50 billion aid package to help the region rebuild. this bill was delayed when the clock ran out. you'll recall at the new year on the legislative session before a vote could be scheduled, which sparked outrage on both sides of the political aisle. tens of thousands of people in new york and new jersey, for starters, are still out of their wrecked homes, or living without adequate heat in the dead of winter.

Source: http://video.msnbc.msn.com/nightly-news/50620916/

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DNA-repairing protein may be key to preventing recurrence of some cancers

Jan. 28, 2013 ? Just as the body can become resistant to antibiotics, certain methods of killing cancer tumors can end up creating resistant tumor cells. But a University of Central Florida professor has found a protein present in several types of cancer, including breast and ovarian cancer, which could be helpful in preventing tumors from coming back.

The protein, KLF8, appears to protect tumor cells from drugs aimed at killing them and even aid the tumor cells' ability to regenerate.

"All cells have a DNA-repair mechanism," explained Jihe Zhao, a medical doctor and researcher who in the past few months has published several articles related to the protein in the Journal of Biological Chemistry and Oncogene, among others. "That's why we survive constant DNA damage threats. But KLF8 is overexpressed in specific cancers, such as breast cancer and ovarian cancer. The thought is that if we can stop it from switching on, we may be able to stop the tumors from coming back as part of therapy. We still need to do a lot more research, but it is plausible.

There are between 2.5 million and 2.7 million women who have breast cancer in the United States and 10 to 20 percent will experience a recurrence, according to the American Cancer Society. Current treatment options, depending on the stage of cancer, include surgical removal followed by chemotherapy using a combination of cancer killing drugs. Each year about 22,200 women are also diagnosed with ovarian cancer.

DNA damage-based chemotherapies depend on failure of cancer cells to repair the DNA damage and subsequent cell death, according to the journal article. Aberrant high levels of DNA repair function in the cells likely increase not only the resistance of the cells to such therapies but also the malignancy of the cells due to improper DNA repair-mediated genomic and chromosomal instability.

In the study, Zhao's team tested one specific cancer-fighting drug used in the treatment of breast cancer to determine the role of the protein.

"Indeed, our results have clearly linked the KLF8-promoted DNA repair to the cell resistance to doxorubicin-induced cell death," Zhao said. "It remains to be determined whether KLF8 plays a similar role in repairing DNA damage caused by other types of genotoxic agents such as DNA alkylating agents and ionizing radiation."

Even so, the results suggest that in addition to enhancing the drug resistance of the cancer cells, KLF8 could play a role in disturbing genomic integrity through its aberrant DNA repair function and subsequently contribute to aggressive progression of cancer.

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Story Source:

The above story is reprinted from materials provided by University of Central Florida.

Note: Materials may be edited for content and length. For further information, please contact the source cited above.

---

Journal References:

1. H. Lu, L. Hu, T. Li, S. Lahiri, C. Shen, M. S. Wason, D. Mukherjee, H. Xie, L. Yu, J. Zhao. A Novel Role of Kruppel-like Factor 8 in DNA Repair in Breast Cancer Cells. Journal of Biological Chemistry, 2012; 287 (52): 43720 DOI: 10.1074/jbc.M112.418053
2. H Lu, X Wang, A M Urvalek, T Li, H Xie, L Yu, J Zhao. Transformation of human ovarian surface epithelial cells by Kr?ppel-like factor 8. Oncogene, 2012; DOI: 10.1038/onc.2012.545

Note: If no author is given, the source is cited instead.

Disclaimer: This article is not intended to provide medical advice, diagnosis or treatment. Views expressed here do not necessarily reflect those of ScienceDaily or its staff.

Source: http://feeds.sciencedaily.com/~r/sciencedaily/~3/OBBSx68vNM4/130128104626.htm

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Brazil blaze recalls pain for RI fire survivors

Argentina, a year later. Thailand in 2008. Russia in 2009.

For survivors of a 2003 Rhode Island nightclub fire that was one of the deadliest in U.S. history, the fire in Brazil that killed hundreds Sunday is the latest in a series of reminders that no matter how far away, those who ignore the lessons of their tragedy can pay a horrible cost.

On a cold night in February 2003, the rock band Great White took the stage at The Station nightclub in West Warwick, R.I. During the show, pyrotechnics set fire to flammable soundproofing foam that lined the walls and ceiling, killing 100 and injuring 200.

Over the decade since, survivors have come together time and again over news of similar disastrous fires overseas.

"We're very tight," said Todd King, one of the survivors. "You can't put into words what we saw."

He said he was woken up Sunday morning by a storm of text messages from others who survived the Rhode Island fire, asking, "Can you believe this is happening again?"

"I'm surprised nobody has learned," he said.

Another Rhode Island survivor, Victoria Eagan, said she and others noted that each of three earlier fires was caused by indoor pyrotechnics igniting with material in the building. Investigators have just begun their work in Brazil, but witnesses said a flare or firework lit by band members may have started the fire.

"I had the same reaction as the other three times," Eagan said Sunday. "We're doomed to repeat history and I wish they could learn."

In the year after the Rhode Island fire, a flare ignited ceiling foam at an overcrowded nightclub in Buenos Aires, Argentina, killing 194 people.

Indoor fireworks were blamed for a fire at a club in Bangkok on New Year's Eve 2008 in which 66 partygoers were killed.

And another indoor fireworks display at a nightclub in Perm, Russia, ignited a plastic ceiling decorated with branches, killing 152 people in December 2009.

In Rhode Island, the Station fire brought about sweeping changes to the state's fire code with one intent: Never again.

Sprinklers are now required in nightclubs and bars with occupancy limits of 100 or more, nightclub workers must be trained in fire safety and more money was set aside for fire safety classes in schools.

Rhode Island also banned pyrotechnics in all but its largest public venues and local fire marshals were enabled to order immediate repairs and write tickets for violations.

Eagan said the changes were necessary in Rhode Island.

"I wish it would spread to other countries," she said.

A deadly blaze overseas does not seem so distant because of the Rhode Island tragedy, Eagan said.

"It's a tragedy that hits close to home," she said. "It's maddening to see it happen again."

In an emailed statement, the Station Fire Memorial Foundation, which is building a memorial to those affected by the 2003 fire, compared the two fires.

"One cannot help but notice the similarities between this tragedy and the Station nightclub fire that occurred nearly 10 years ago," the group said.

Source: http://news.yahoo.com/brazil-blaze-recalls-pain-ri-fire-survivors-174616136.html

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Blog Prompt Monday: Getting Into A Technology-Focused Career ...

By Kathryn Magura

Happy Monday everyone! Today?s blog prompt is one that resonates with me, because it allows me to share my accidental journey into the world of technology.

How do you get into the technology field without a background in technology?

Well, the honest answer to this question is quite simply: you get out there and do it! Not quite as helpful as you hoped? Well, let me share my story with you then. I went to college knowing I would receive a degree in some sort of Liberal Arts area. I was drawn to Psychology, so I pursued that as my major. Early on in college, I remember meeting with an academic advisor to determine if I wanted to go for a Bachelor of Arts or Sciences. The gist was: a Bachelor of Arts required a second language, and a Bachelor of Science required computer classes and more science classes.

For me, there was no real decision to make. I had taken German in high school, and figured I would take a couple of years of it at the college level and fulfill my Bachelor of Arts requirements. Why on earth would I put myself through the rigors of a Bachelor of Science degree when I refused to take computer classes. That?s right, I refused to take computer classes.

Don?t get me wrong, I loved my computer. I had been surfing the internet before it was really in style. My family had also had a computer for my brother and I to write our high school papers on way before many other families could afford one. That said, the actual technology behind computers scared me. I?m not sure when I came to this conclusion, but it seemed like I had always known I was never good with technology.

In retrospect, it seems really sad that I never trusted my abilities when it came to technology. Even when I had always had a natural ability to learn and use a variety of technologies. I was always the one to program our family VCR growing up, and had even helped my father (the engineer, it should be noted) reprogram his air conditioner when it wasn?t working right. Yet for some reason, I always felt dumb when in came to computers.

My senior year of college, I had the opportunity to work in the Housing office. While the work focused heavily on customer service, it also required me to use the University information system and Microsoft excel a lot. I was fearful of looking dumb for not knowing how to use the technology, but I jumped right in with an eagerness to learn. As I started to learn the ropes, I was surprised to see what a natural I was with the technology. Not only did I pick up the systems with ease, I was able to train others! Where the heck did this ability come from?

Flash forward a few years to about a week ago. One of our resident directors needed some help pulling data together for a meeting. I had some time available in my calendar, so I invited him over for a lesson on the greatness of excel. As I was pulling the data together from the University data warehousing system, I could see his jaw sort of frozen as I swiftly shifted from one screen to the next (side note, dual monitors are a true godsend) to capture all the data needed. I then switched over to excel where we put the data into pivot tables, charts and graphs.

As I was training, I could hear the excitement in my voice. Who knew I could get so excited by a pivot table?? I even took time to send out this tweet:

After we had pulled all the data needed together for the meeting, the RD looked at me (a little glazed over. Whoops.) and asked if I had always been this good with technology. I simply stated that no, I had not been, and had actually been afraid of it for the longest time. It took pushing myself past my comfort zone by just getting in there and using it for me to actually learn that I was indeed quite skilled with technology.

My point in sharing this story is to encourage others to take the technology leap. Get out there and test the waters! Don?t feel comfortable with the Microsoft Office suite? Get out there and take a training course! Most are either free or inexpensive. There may also be people out there willing to share their knowledge with you, if you are willing to seek them out. Trust me, if I can get over my own fear of using technology you can too!

So what?s your technology story? What advice do you have for others who want to get into the field of technology?

Tags: #sawomenblog, #sawtt, technology, women, women in technology

This entry was posted on January 28, 2013 at 11:00 am. You can follow any responses to this entry through the RSS 2.0 feed. You can leave a response, or trackback from your own site.

Posted in Prompts by kmagura

Source: http://sawomentalktech.com/blog/2013/01/28/blog-prompt-monday-getting-into-a-technology-focused-career/

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Residential and Business Security | Save The Knoll

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Source: http://savetheknoll.org/residential-and-business-security/

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My Yeast Let Me Down: A Love Song

In a moment, there's going to be singing. It will be a love song, sung by Nathaniel, a sad-eyed, blue-gloved scientist who gave his heart to an organism, but then did her wrong. (Or maybe she did him wrong. These things get complicated.)

Like every lost love, this one has a back story. I don't know Berkeley biologist Nathaniel Krefman, but I can guess what happened. It happens all the time.

Imagining The Young Nathaniel ...

You fall in love with science, there's a professor who takes you on, leads you to a good graduate program, you study hard, spend your 20s earning embarrassingly little money working crazy hours, not minding that much, you get your Ph.D., you're trained, you're primed and suddenly you're in a job market where there's one academic opening for every five new Ph.D.s ? and you're scared, your colleagues start to bail, slip off to med school, business school, and that dream you had ? being a post-doc in a good lab, with a bench, and a little freedom? That's next to impossible ? but, but, but, you hang on, and hooray! You get a starter job, get an idea, write it down, send it off to some National Institute in Washington, or to a Foundation, and double-hooray! They fund you, and now, finally, you've got a little money, a little time ... and then this happens ...

Your experiment fails.

Bad, Bad Yeast

The thing you thought would happen doesn't. Maybe it's something stupid, like your yeast won't grow, and you need them to run your trials. You want to try again, with a different critter, but that means another National Institutes of Health grant and Washington says, ... well ... if you were working on cancer, or STDs, or flu, a disease everybody's heard of, then maybe we'd give you more money ... but you're not.

You're just chasing a cool, fascinating idea. And it seems you chose the wrong yeast to do it with. That's when you walk into your lab, pack up your test tubes, your flasks, your dishes, your notes, and you sing this sad, sad song ...

Thanks to Nathaniel Krefman, Lydia The, Haomiao Huang at Berkeley for the video. This is our second homage to musicians Gotye and Kimbra; a few months ago we blogged about the cool camouflage designs they included in their video. And thanks to physics grad student and blogger Aatish Bhatia at Rutgers who notices first what I then notice later.

Source: http://www.npr.org/blogs/krulwich/2013/01/28/170457572/my-yeast-let-me-down-a-love-song?ft=1&f=1007

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